Protein name:
Toll-like receptor 9 ;
Alternative:
CD:
CD289 ;
Organism:
Pig (Sus scrofa).
General Annotation
Sub Unit:
Interacts with MYD88 via their respective TIR domains (By similarity). Interacts with BTK and CNPY3 (By similarity). Interacts (via transmembrane domain) with UNC93B1.
Function:
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Subcellular Location:
Endoplasmic reticulum membrane
Single-pass type I membrane protein
Endosome
Lysosome
Cytoplasmic vesicle
phagosome
Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
Protein Attributes:
50:
MGPRCTLHPL | SLLVQVTALA | AALAQGRLPA | FLPCELQPHG | LVNCNWLFLK |
100:
SVPHFSAAAP | RANVTSLSLL | SNRIHHLHDS | DFVHLSSLRT | LNLKWNCPPA |
150:
GLSPMHFPCH | MTIEPNTFLA | VPTLEELNLS | YNSITTVPAL | PDSLVSLSLS |
200:
RTNILVLDPT | HLTGLHALRY | LYMDGNCYYK | NPCQGALEVV | PGALLGLGNL |
250:
THLSLKYNNL | TEVPRSLPPS | LETLLLSYNH | IVTLTPEDLA | NLTALRVLDV |
300:
GGNCRRCDHA | RNPCRECPKD | HPKLHSDTFS | HLSRLEGLVL | KDSSLYNLDT |
350:
RWFRGLDRLQ | VLDLSENFLY | DCITKTTAFQ | GLARLRSLNL | SFNYHKKVSF |
400:
AHLHLAPSFG | HLRSLKELDM | HGIFFRSLSE | TTLQPLVQLP | MLQTLRLQMN |
450:
FINQAQLSIF | GAFPGLLYVD | LSDNRISGAA | RPVAITREVD | GRERVWLPSR |
500:
NLAPRPLDTL | RSEDFMPNCK | AFSFTLDLSR | NNLVTIQSEM | FARLSRLECL |
550:
RLSHNSISQA | VNGSQFVPLT | SLRVLDLSHN | KLDLYHGRSF | TELPRLEALD |
600:
LSYNSQPFTM | QGVGHNLSFV | AQLPALRYLS | LAHNDIHSRV | SQQLCSASLC |
650:
ALDFSGNDLS | RMWAEGDLYL | RFFQGLRSLV | WLDLSQNHLH | TLLPRALDNL |
700:
PKSLKHLHLR | DNNLAFFNWS | SLTLLPKLET | LDLAGNQLKA | LSNGSLPSGT |
750:
QLRRLDLSGN | SIGFVNPGFF | ALAKQLEELN | LSANALKTVE | PSWFGSMVGN |
800:
LKVLDVSANP | LHCACGATFV | GFLLEVQAAV | PGLPSRVKCG | SPGQLQGHSI |
850:
FAQDLRLCLD | ETLSWNCFGI | SLLAMALGLV | VPMLHHLCGW | DLWYCFHLCL |
900:
AWLPHRGQRR | GADALFYDAF | VVFDKAQSAV | ADWVYNELRV | QLEERRGRRA |
950:
LRLCLEERDW | LPGKTLFENL | WASVYSSRKT | LFVLAHTDRV | SGLLRASFLL |
1000:
AQQRLLEDRK | DVVVLVILRP | DAYRSRYVRL | RQRLCRQSVL | LWPHQPRGQG |
1030:
SFWAQLGTAL | TRDNHHFYNR | NFCRGPTTAE |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Pig
Dog
Mouse
Bovine
ELISA Kit for Pig Toll-like receptor 9
ELISA Kit for Pig Toll-like receptor 9
ELISA Kit for Pig Toll-like receptor 9
ELISA Kit for Pig Toll-like receptor 9
ELISA Kit for Pig Toll-like receptor 9
CLIA Kit for Pig Toll-like receptor 9
CLIA Kit for Pig Toll-like receptor 9
CLIA Kit for Pig Toll-like receptor 9
CLIA Kit for Pig Toll-like receptor 9
CLIA Kit for Pig Toll-like receptor 9
Polyclonal Antibody for Pig Toll-like receptor 9
Polyclonal Antibody for Pig Toll-like receptor 9
Polyclonal Antibody for Pig Toll-like receptor 9
Polyclonal Antibody for Pig Toll-like receptor 9
Polyclonal Antibody for Pig Toll-like receptor 9
Monoclonal Antibody for Pig Toll-like receptor 9
Monoclonal Antibody for Pig Toll-like receptor 9
Monoclonal Antibody for Pig Toll-like receptor 9
Monoclonal Antibody for Pig Toll-like receptor 9
Monoclonal Antibody for Pig Toll-like receptor 9
Protein for Pig Toll-like receptor 9
Protein for Pig Toll-like receptor 9
Protein for Pig Toll-like receptor 9
Protein for Pig Toll-like receptor 9
Protein for Pig Toll-like receptor 9
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Spleen .